Lars1 - leucyl-tRNA synthetase 1

Predicted to enable GTPase activator activity; glutamine-tRNA ligase activity; and leucine-tRNA ligase activity. Predicted to be involved in several processes, including cellular response to leucine; cellular response to leucine starvation; and tRNA aminoacylation for protein translation. Predicted to be located in several cellular components, including endoplasmic reticulum; lysosome; and nuclear body. Predicted to be part of aminoacyl-tRNA synthetase multienzyme complex. Human ortholog(s) of this gene implicated in infantile liver failure syndrome 1. Orthologous to human LARS1 (leucyl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]