Gcm2 - glial cells missing transcription factor 2

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including cellular ion homeostasis; gliogenesis; and transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including cellular response to organic substance; negative regulation of apoptotic process; and parathyroid gland development. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in familial isolated hypoparathyroidism and hyperparathyroidism. Orthologous to human GCM2 (glial cells missing transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]