Dr1 - down-regulator of transcription 1

Predicted to enable RNA polymerase II general transcription initiation factor activity; TBP-class protein binding activity; and core promoter sequence-specific DNA binding activity. Predicted to be involved in several processes, including RNA polymerase II preinitiation complex assembly; histone H3 acetylation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of ATAC complex; RNA polymerase II transcription regulator complex; and negative cofactor 2 complex. Orthologous to human DR1 (down-regulator of transcription 1). [provided by Alliance of Genome Resources, Apr 2022]