Glmn - glomulin, FKBP associated protein

Predicted to enable hepatocyte growth factor receptor binding activity; ubiquitin protein ligase binding activity; and ubiquitin-protein transferase inhibitor activity. Predicted to be involved in several processes, including negative regulation of T cell proliferation; regulation of gene expression; and vasculogenesis. Predicted to act upstream of or within several processes, including neural tube closure; positive regulation of interleukin-2 production; and regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of Cul2-RING ubiquitin ligase complex; Cul3-RING ubiquitin ligase complex; and Cul4A-RING E3 ubiquitin ligase complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in arteriovenous malformation and glomus tumor. Orthologous to human GLMN (glomulin, FKBP associated protein). [provided by Alliance of Genome Resources, Apr 2022]