Fcgr2b - Fc gamma receptor 2B

Enables IgG binding activity. Involved in several processes, including cellular response to amyloid-beta; cellular response to lipopolysaccharide; and negative regulation of neutrophil apoptotic process. Located in cell surface; membrane raft; and recycling endosome. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dengue disease (multiple); hematologic cancer (multiple); leukopenia (multiple); and malaria (multiple). Orthologous to several human genes including FCGR2B (Fc fragment of IgG receptor IIb). [provided by Alliance of Genome Resources, Apr 2022]