Kiss1 - KiSS-1 metastasis-suppressor

Enables kisspeptin receptor binding activity. Involved in several processes, including generation of ovulation cycle rhythm; positive regulation of cell communication; and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Located in several cellular components, including apical plasma membrane; extracellular space; and neuronal cell body. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 13 with or without anosmia. Orthologous to human KISS1 (KiSS-1 metastasis suppressor). [provided by Alliance of Genome Resources, Apr 2022]