Iscu - iron-sulfur cluster assembly enzyme

Predicted to enable 2 iron, 2 sulfur cluster binding activity; ferrous iron binding activity; and molecular adaptor activity. Predicted to be involved in several processes, including negative regulation of iron ion import across plasma membrane; positive regulation of aconitate hydratase activity; and positive regulation of mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in cytosol and mitochondrion. Predicted to be active in mitochondrial matrix. Orthologous to human ISCU (iron-sulfur cluster assembly enzyme). [provided by Alliance of Genome Resources, Apr 2022]