Tfr2 - transferrin receptor 2

Predicted to enable co-receptor binding activity and transferrin receptor activity. Involved in acute-phase response. Predicted to be located in cytoplasmic vesicle. Predicted to be integral component of plasma membrane. Predicted to be part of HFE-transferrin receptor complex. Predicted to be active in external side of plasma membrane. Used to study hemochromatosis type 3. Human ortholog(s) of this gene implicated in hemochromatosis and hemochromatosis type 3. Orthologous to human TFR2 (transferrin receptor 2). [provided by Alliance of Genome Resources, Apr 2022]