Predicted to enable ribosomal large subunit binding activity and ubiquitin protein ligase activity. Predicted to be involved in protein autoubiquitination; rescue of stalled ribosome; and ribosome-associated ubiquitin-dependent protein catabolic process. Predicted to be part of RQC complex. Predicted to be active in cytosol. Orthologous to human LTN1 (listerin E3 ubiquitin protein ligase 1). [provided by Alliance of Genome Resources, Apr 2022]