Eftud2 - elongation factor Tu GTP binding domain containing 2

Predicted to enable GTPase activity and U5 snRNA binding activity. Involved in cellular response to xenobiotic stimulus and response to cocaine. Predicted to be located in Cajal body and nuclear speck. Predicted to be part of U2-type catalytic step 2 spliceosome; U2-type precatalytic spliceosome; and U4/U6 x U5 tri-snRNP complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in esophageal atresia and mandibulofacial dysostosis, Guion-Almeida type. Orthologous to human EFTUD2 (elongation factor Tu GTP binding domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]