Enables protein serine/threonine kinase activity. Involved in negative regulation of sodium ion transport and protein phosphorylation. Located in cytosol and membrane. Biomarker of transient cerebral ischemia. Human ortholog(s) of this gene implicated in hypertension and pseudohypoaldosteronism. Orthologous to human WNK4 (WNK lysine deficient protein kinase 4). [provided by Alliance of Genome Resources, Apr 2022]