Mks1 - MKS transition zone complex subunit 1

Predicted to be involved in branching morphogenesis of an epithelial tube and cilium assembly. Predicted to act upstream of or within several processes, including chordate embryonic development; plasma membrane bounded cell projection organization; and regulation of signal transduction. Predicted to be located in several cellular components, including ciliary transition zone; cytoplasm; and microtubule organizing center. Predicted to be part of MKS complex. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 13; Joubert syndrome 28; and Meckel syndrome 1. Orthologous to human MKS1 (MKS transition zone complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022]