Aloxe3 - arachidonate lipoxygenase 3

Predicted to enable hepoxilin A3 synthase activity; intramolecular transferase activity, transferring hydroxy groups; and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. Involved in arachidonic acid metabolic process; hepoxilin biosynthetic process; and sensory perception of pain. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 1 and autosomal recessive congenital ichthyosis 3. Orthologous to human ALOXE3 (arachidonate lipoxygenase 3). [provided by Alliance of Genome Resources, Apr 2022]