Nlrc3 - NLR family, CARD domain containing 3

Predicted to enable phosphatidylinositol 3-kinase regulatory subunit binding activity. Predicted to be involved in several processes, including negative regulation of cell population proliferation; negative regulation of cytokine production; and negative regulation of intracellular signal transduction. Predicted to act upstream of or within regulation of protein ubiquitination and response to lipopolysaccharide. Predicted to be located in centriolar satellite; intracellular membrane-bounded organelle; and perinuclear region of cytoplasm. Predicted to be active in cytosol. Orthologous to human NLRC3 (NLR family CARD domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]