Sgpl1 - sphingosine-1-phosphate lyase 1

Predicted to enable sphinganine-1-phosphate aldolase activity. Predicted to be involved in apoptotic signaling pathway; fatty acid metabolic process; and sphingolipid metabolic process. Predicted to act upstream of or within several processes, including animal organ development; cellular hormone metabolic process; and face morphogenesis. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in nephrotic syndrome type 14. Orthologous to human SGPL1 (sphingosine-1-phosphate lyase 1). [provided by Alliance of Genome Resources, Apr 2022]