Kiss1 - KiSS-1 metastasis-suppressor

Predicted to enable kisspeptin receptor binding activity. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; decidualization; and negative regulation of cell migration. Predicted to be located in several cellular components, including apical plasma membrane; extracellular space; and neuronal cell body. Predicted to be active in neuron projection. Is expressed in diencephalon and metanephros. Used to study hypogonadotropic hypogonadism 13 with or without anosmia. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 13 with or without anosmia. Orthologous to human KISS1 (KiSS-1 metastasis suppressor). [provided by Alliance of Genome Resources, Apr 2022]