Predicted to enable chloride channel inhibitor activity; potassium channel inhibitor activity; and protein serine/threonine kinase activity. Involved in negative regulation of pancreatic juice secretion. Acts upstream of or within cell volume homeostasis and maintenance of blood-brain barrier. Located in adherens junction and bicellular tight junction. Orthologous to human WNK3 (WNK lysine deficient protein kinase 3). [provided by Alliance of Genome Resources, Apr 2022]