Depdc5 - DEP domain containing 5

Predicted to contribute to GTPase activator activity. Predicted to be involved in cellular response to amino acid starvation; negative regulation of TORC1 signaling; and regulation of autophagy. Located in cytosol and perinuclear region of cytoplasm. Is expressed in branchial arch; genitourinary system; limb; and peripheral nervous system. Human ortholog(s) of this gene implicated in focal epilepsy. Orthologous to human DEPDC5 (DEP domain containing 5, GATOR1 subcomplex subunit). [provided by Alliance of Genome Resources, Apr 2022]