Trpa1 - transient receptor potential cation channel, subfamily A, member 1

Enables calcium channel activity. Involved in several processes, including cell surface receptor signaling pathway; cellular calcium ion homeostasis; and response to organic cyclic compound. Acts upstream of or within several processes, including detection of stimulus involved in sensory perception of pain; response to hydrogen peroxide; and thermoception. Located in stereocilium bundle. Is expressed in cochlea and glossopharyngeal ganglion. Human ortholog(s) of this gene implicated in familial episodic pain syndrome 1. Orthologous to human TRPA1 (transient receptor potential cation channel subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]