Naglu - alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)

Predicted to enable alpha-N-acetylglucosaminidase activity. Acts upstream of or within several processes, including cerebellar Purkinje cell layer development; locomotor rhythm; and sensory organ development. Predicted to be located in extracellular exosome. Used to study mucopolysaccharidosis III and otitis media. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2V; mucopolysaccharidosis III; and mucopolysaccharidosis type IIIB. Orthologous to human NAGLU (N-acetyl-alpha-glucosaminidase). [provided by Alliance of Genome Resources, Apr 2022]