Tnfrsf12a - tumor necrosis factor receptor superfamily, member 12a

Involved in regulation of angiogenesis. Acts upstream of or within extrinsic apoptotic signaling pathway; positive regulation of axon extension; and substrate-dependent cell migration, cell attachment to substrate. Located in cell surface; plasma membrane; and ruffle. Is expressed in several structures, including adrenal medulla; genitourinary system; heart; limb long bone; and molar. Orthologous to human TNFRSF12A (TNF receptor superfamily member 12A). [provided by Alliance of Genome Resources, Apr 2022]