Enables eukaryotic translation initiation factor 2alpha kinase activity. Predicted to be involved in several processes, including HRI-mediated signaling; negative regulation of hemoglobin biosynthetic process; and response to iron ion starvation. Predicted to act upstream of or within several processes, including macrophage differentiation; protoporphyrinogen IX metabolic process; and regulation of cellular macromolecule biosynthetic process. Predicted to be located in cytoplasm. Orthologous to human EIF2AK1 (eukaryotic translation initiation factor 2 alpha kinase 1). [provided by Alliance of Genome Resources, Apr 2022]