Ankrd1 - ankyrin repeat domain 1

Predicted to enable several functions, including R-SMAD binding activity; histone deacetylase binding activity; and p53 binding activity. Involved in several processes, including cellular response to hypoxia; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron projection development. Located in I band and nucleus. Human ortholog(s) of this gene implicated in congenital structural myopathy; dilated cardiomyopathy; hypertrophic cardiomyopathy; nemaline myopathy; and spinal muscular atrophy. Orthologous to human ANKRD1 (ankyrin repeat domain 1). [provided by Alliance of Genome Resources, Apr 2022]