Irf2bp2 - interferon regulatory factor 2 binding protein 2

Predicted to enable transcription corepressor activity. Predicted to be involved in immature B cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including brain; diaphragm; liver; lung; and musculature. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human IRF2BP2 (interferon regulatory factor 2 binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]