Nup98 - nucleoporin 98

Predicted to enable several functions, including nuclear localization sequence binding activity; promoter-specific chromatin binding activity; and transcription coactivator activity. Predicted to be a structural constituent of nuclear pore. Predicted to be involved in nuclear pore complex assembly; positive regulation of mRNA splicing, via spliceosome; and protein import into nucleus. Predicted to act upstream of or within mRNA transport; protein transport; and proteolysis. Located in nucleus. Is expressed in several structures, including nervous system and neural retina. Human ortholog(s) of this gene implicated in T-cell acute lymphoblastic leukemia. Orthologous to human NUP98 (nucleoporin 98 and 96 precursor). [provided by Alliance of Genome Resources, Apr 2022]