Pon3 - paraoxonase 3

Predicted to enable 3,4-dihydrocoumarin hydrolase activity; arylesterase activity; and protein homodimerization activity. Involved in negative regulation of superoxide anion generation. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in Alzheimer's disease; amyotrophic lateral sclerosis; and atherosclerosis. Orthologous to human PON3 (paraoxonase 3). [provided by Alliance of Genome Resources, Apr 2022]