Clspn - claspin

Predicted to enable DNA secondary structure binding activity and anaphase-promoting complex binding activity. Predicted to be involved in activation of protein kinase activity; mitotic G2/M transition checkpoint; and peptidyl-serine phosphorylation. Predicted to act upstream of or within DNA replication checkpoint signaling. Predicted to be located in Golgi apparatus and nucleoplasm. Is expressed in several structures, including adrenal medulla; brain ventricular layer; oral epithelium; reproductive system; and trunk mesenchyme derived from neural crest. Orthologous to human CLSPN (claspin). [provided by Alliance of Genome Resources, Apr 2022]