Map4k4 - mitogen-activated protein kinase kinase kinase kinase 4
Alias:
HGK
Nik
9430080K19Rik
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Sequence Homology
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Enables ATP binding activity and protein serine/threonine kinase activity. Involved in several processes, including positive regulation of cell-substrate junction organization; positive regulation of intracellular signal transduction; and positive regulation of keratinocyte migration. Located in focal adhesion. Is expressed in several structures, including genitourinary system; molar; nervous system; neural retina; and skin. Orthologous to human MAP4K4 (mitogen-activated protein kinase kinase kinase kinase 4). [provided by Alliance of Genome Resources, Apr 2022]