Figla - folliculogenesis specific basic helix-loop-helix

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Is expressed in follicle cell of primary follicle; oocyte of primary follicle; oocyte of secondary follicle; and ovary. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 6. Orthologous to human FIGLA (folliculogenesis specific bHLH transcription factor). [provided by Alliance of Genome Resources, Apr 2022]