Sh3rf2 - SH3 domain containing ring finger 2

Predicted to enable protein phosphatase 1 binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including protein autoubiquitination; regulation of JNK cascade; and regulation of cellular protein metabolic process. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Is expressed in central nervous system; dorsal root ganglion; and neural retina. Used to study autism spectrum disorder. Orthologous to human SH3RF2 (SH3 domain containing ring finger 2). [provided by Alliance of Genome Resources, Apr 2022]