Ctsj - cathepsin J

Predicted to enable several functions, including collagen binding activity; fibronectin binding activity; and serpin family protein binding activity. Predicted to be involved in several processes, including collagen catabolic process; proteolysis; and viral entry into host cell. Predicted to be located in Golgi apparatus; multivesicular body; and plasma membrane. Predicted to be active in extracellular space and lysosome. Predicted to colocalize with perinuclear region of cytoplasm. Is expressed in ectoplacental cone; embryo; extraembryonic component; placenta; and yolk sac. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy. Orthologous to human CTSL (cathepsin L). [provided by Alliance of Genome Resources, Apr 2022]