Ltbp1 - latent transforming growth factor beta binding protein 1

Predicted to enable microfibril binding activity and transforming growth factor beta binding activity. Acts upstream of or within aorta development; coronary vasculature development; and ventricular septum development. Located in microfibril. Is expressed in several structures, including embryo mesenchyme; genitourinary system; heart; integumental system; and neural ectoderm. Human ortholog(s) of this gene implicated in cutis laxa. Orthologous to human LTBP1 (latent transforming growth factor beta binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]