Nrip1 - nuclear receptor interacting protein 1

Enables several functions, including histone deacetylase binding activity; retinoid X receptor binding activity; and transcription coactivator activity. Involved in circadian regulation of gene expression; lipid storage; and ovarian follicle rupture. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nuclear speck. Part of histone deacetylase complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in CAKUT and osteoporosis. Orthologous to human NRIP1 (nuclear receptor interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]