Enables NADPH:quinone reductase activity; alcohol dehydrogenase activity, zinc-dependent; and alditol:NADP+ 1-oxidoreductase activity. Involved in fatty acid omega-oxidation. Acts upstream of or within several processes, including alcohol catabolic process; ethanol metabolic process; and quinone metabolic process. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including adrenal cortex; genitourinary system; integumental system; limb; and nervous system. Orthologous to human ADH4 (alcohol dehydrogenase 4 (class II), pi polypeptide). [provided by Alliance of Genome Resources, Apr 2022]