Ccnb1 - cyclin B1

Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity; enzyme binding activity; and patched binding activity. Acts upstream of or within several processes, including histone H3-S10 phosphorylation involved in chromosome condensation; in utero embryonic development; and positive regulation of fibroblast proliferation. Located in cytoplasm; membrane; and nucleus. Colocalizes with mitochondrial matrix. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; eye; and genitourinary system. Human ortholog(s) of this gene implicated in breast cancer and prostate cancer. Orthologous to human CCNB1 (cyclin B1). [provided by Alliance of Genome Resources, Apr 2022]