Eme1 - essential meiotic structure-specific endonuclease 1

Predicted to enable DNA binding activity; endonuclease activity; and metal ion binding activity. Predicted to be involved in DNA metabolic process and mitotic intra-S DNA damage checkpoint signaling. Predicted to act upstream of or within response to intra-S DNA damage checkpoint signaling. Located in heterochromatin. Is expressed in several structures, including adrenal medulla; respiratory system; sensory organ; skeleton; and trunk mesenchyme derived from neural crest. Orthologous to human EME1 (essential meiotic structure-specific endonuclease 1). [provided by Alliance of Genome Resources, Apr 2022]