Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in adrenal gland; cerebral cortex mantle layer; and vertebral axis musculature. Orthologous to human RNF217 (ring finger protein 217). [provided by Alliance of Genome Resources, Apr 2022]