Enables sterol O-acyltransferase activity. Involved in cholesterol metabolic process and response to nutrient. Located in endoplasmic reticulum. Used to study end stage renal disease. Biomarker of nephrotic syndrome. Human ortholog(s) of this gene implicated in coronary artery disease and hepatocellular carcinoma. Orthologous to human SOAT2 (sterol O-acyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]