Hspa4 - heat shock protein family A (Hsp70) member 4

Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including negative regulation of DNA binding activity; negative regulation of macromolecule metabolic process; and positive regulation of angiogenesis. Located in cytosol; lipid droplet; and nucleus. Used to study adult respiratory distress syndrome and middle cerebral artery infarction. Biomarker of Parkinson's disease and liver benign neoplasm. Human ortholog(s) of this gene implicated in Chagas disease. Orthologous to human HSPA4 (heat shock protein family A (Hsp70) member 4). [provided by Alliance of Genome Resources, Apr 2022]