Fzd3 - frizzled class receptor 3

Predicted to enable PDZ domain binding activity; Wnt-activated receptor activity; and Wnt-protein binding activity. Involved in brain development; response to electrical stimulus; and response to xenobiotic stimulus. Predicted to be located in several cellular components, including apical plasma membrane; filopodium tip; and lateral plasma membrane. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Predicted to colocalize with presynaptic active zone. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome and schizophrenia. Orthologous to human FZD3 (frizzled class receptor 3). [provided by Alliance of Genome Resources, Apr 2022]