Myo7a - myosin VIIA

Enables several functions, including adenyl ribonucleotide binding activity; calmodulin binding activity; and identical protein binding activity. Involved in actin filament-based movement. Located in cytoplasm; microvillus; and upper tip-link density. Part of myosin VII complex. Used to study Usher syndrome. Human ortholog(s) of this gene implicated in Leber congenital amaurosis; Usher syndrome (multiple); auditory system disease (multiple); and congenital nystagmus. Orthologous to human MYO7A (myosin VIIA). [provided by Alliance of Genome Resources, Apr 2022]