Slc27a4 - solute carrier family 27 (fatty acid transporter), member 4

Enables oleoyl-CoA ligase activity and very long-chain fatty acid-CoA ligase activity. Involved in glucose import in response to insulin stimulus; long-chain fatty acid import into cell; and negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity. Acts upstream of or within fatty acid metabolic process; lipid transport; and skin development. Located in brush border membrane; endoplasmic reticulum; and microvillus. Is expressed in several structures, including alimentary system; eye; liver; nervous system; and urinary system. Used to study lethal restrictive dermopathy. Orthologous to human SLC27A4 (solute carrier family 27 member 4). [provided by Alliance of Genome Resources, Apr 2022]