Orc4 - origin recognition complex, subunit 4

Predicted to enable DNA replication origin binding activity and nucleotide binding activity. Predicted to be involved in DNA replication initiation. Predicted to act upstream of or within DNA replication. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of nuclear origin of replication recognition complex. Predicted to colocalize with chromosome, telomeric region. Is expressed in brain; embryo; and pancreas epithelium. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 2. Orthologous to human ORC4 (origin recognition complex subunit 4). [provided by Alliance of Genome Resources, Apr 2022]