Map3k8 - mitogen-activated protein kinase kinase kinase 8
Alias:
Cot
Est
Estf
Tpl2
Tpl-2
c-COT
Cot/Tpl2
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Predicted to enable MAP kinase kinase kinase activity. Predicted to be involved in protein phosphorylation and signal transduction. Predicted to act upstream of or within immune system process and phosphorylation. Predicted to be located in cytosol. Is expressed in several structures, including adipose tissue; adrenal gland; alimentary system; hemolymphoid system gland; and reproductive system. Orthologous to human MAP3K8 (mitogen-activated protein kinase kinase kinase 8). [provided by Alliance of Genome Resources, Apr 2022]