Predicted to enable several functions, including ATP binding activity; JUN kinase kinase kinase activity; and enzyme binding activity. Predicted to be involved in several processes, including JNK cascade; positive regulation of MAPK cascade; and positive regulation of neuron apoptotic process. Predicted to act upstream of or within phosphorylation. Predicted to be located in microtubule. Predicted to be active in centrosome. Is expressed in blood vessel and brain. Orthologous to human MAP3K11 (mitogen-activated protein kinase kinase kinase 11). [provided by Alliance of Genome Resources, Apr 2022]