Map2k2 - mitogen-activated protein kinase kinase 2
Alias:
MK2
MEK2
Prkmk2
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Enables molecular adaptor activity. Involved in positive regulation of cell motility. Acts upstream of or within several processes, including ERK1 and ERK2 cascade; animal organ development; and regulation of neuron projection development. Located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in cardiofaciocutaneous syndrome 4 and small intestine adenocarcinoma. Orthologous to human MAP2K2 (mitogen-activated protein kinase kinase 2). [provided by Alliance of Genome Resources, Apr 2022]