Map2k2 - mitogen-activated protein kinase kinase 2

Enables molecular adaptor activity. Involved in positive regulation of cell motility. Acts upstream of or within several processes, including ERK1 and ERK2 cascade; animal organ development; and regulation of neuron projection development. Located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in cardiofaciocutaneous syndrome 4 and small intestine adenocarcinoma. Orthologous to human MAP2K2 (mitogen-activated protein kinase kinase 2). [provided by Alliance of Genome Resources, Apr 2022]