Acts upstream of or within positive regulation of JNK cascade. Predicted to be located in cytoplasm; mitotic spindle pole; and nuclear lumen. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and integumental system. Human ortholog(s) of this gene implicated in nephronophthisis 20. Orthologous to human MAPKBP1 (mitogen-activated protein kinase binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]