Nf2 - NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

Enables beta-catenin binding activity; integrin binding activity; and protein domain specific binding activity. Involved in negative regulation of cell growth. Located in several cellular components, including membrane raft; perinuclear region of cytoplasm; and synapse. Part of protein-containing complex. Biomarker of epilepsy. Human ortholog(s) of this gene implicated in familial meningioma; neurilemmomatosis; and neurofibromatosis 2. Orthologous to human NF2 (NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor). [provided by Alliance of Genome Resources, Apr 2022]