Enables neuropeptide hormone activity; type 1 hypocretin receptor binding activity; and type 2 hypocretin receptor binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; regulation of metal ion transport; and regulation of transmission of nerve impulse. Located in secretory granule. Biomarker of hyperglycemia and obesity. Human ortholog(s) of this gene implicated in narcolepsy. Orthologous to human HCRT (hypocretin neuropeptide precursor). [provided by Alliance of Genome Resources, Apr 2022]