Ucp3 - uncoupling protein 3

Predicted to enable oxidative phosphorylation uncoupler activity. Involved in several processes, including response to activity; response to insulin; and response to superoxide. Located in mitochondrion. Used to study type 2 diabetes mellitus. Biomarker of congestive heart failure; hypertension; hyperthyroidism; hypothyroidism; and prediabetes syndrome. Human ortholog(s) of this gene implicated in coronary restenosis; diabetic neuropathy; glucose metabolism disease (multiple); and obesity. Orthologous to human UCP3 (uncoupling protein 3). [provided by Alliance of Genome Resources, Apr 2022]